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Cancer of the nose, mouth, lips, gums, tongue, throat, voicebox and other sites. What causes head and neck cancer: Smoking, cigarettes, cigars, pipes, chewing tobacco, snuff, ionizing Radiation, EB virus, HPV How do I know about cancer: 1. Swelling or sore that does not heal, the most common symptom 2. Red or white patch in the mouth 3. Lump, bump, or mass in the head or neck area, with or without pain 4. Persistent sore throat 5. Foul mouth odor not explained by hygiene 6. Hoarseness or change in voice 7. Nasal obstruction or persistent nasal congestion 8. Frequent nose bleeds and/or unusual nasal discharge 9. Difficulty breathing 10. Double vision 11. Numbness or weakness of a body part in the head and neck region 12. Pain or difficulty chewing, swallowing, or moving the jaws or tongue 13. Ear and/or jaw pain 14. Blood in the saliva or phlegm, which is mucus discharged in mouth from respiratory passages 15. Loosening of teeth 16. Dentures that no longer fit 17. Unexplained weight loss 18. Fatigue